Semaglutide is a synthetic analogue of human glucagon-like peptide-1 (GLP-1) that functions as a GLP-1 receptor agonist. It has been studied for its effects on glucose-dependent insulin signaling, glucagon regulation, gastric emptying, appetite signaling, and energy balance.
Structure: 31-amino-acid peptide analogue conjugated to a C18 fatty diacid side chain
Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉
Molecular Weight: Approximately 4,113.6 g/mol
Receptor Activity: GLP-1 receptor agonist
Research Focus: GLP-1 receptor signaling, glucose homeostasis, and metabolic pathways
Research Use Only: Not intended for human or veterinary use.