Glutathione

Glutathione: Research Use Only

Product Overview

Glutathione is a naturally occurring tripeptide composed of glutamic acid, cysteine, and glycine. It is supplied for controlled laboratory investigation involving cellular redox chemistry, thiol-dependent reactions, enzymatic activity, and oxidative-stress pathways.

The compound exists primarily in reduced and oxidized forms. Reduced glutathione is abbreviated GSH, while its oxidized disulfide form is known as glutathione disulfide or GSSG.

Molecular Profile

• Compound: Reduced L-glutathione
• Abbreviation: GSH
• Sequence: γ-L-glutamyl-L-cysteinylglycine
• Molecular formula: C₁₀H₁₇N₃O₆S
• Molecular weight: Approximately 307.32 g/mol
• Compound class: Naturally occurring tripeptide
• Oxidized form: Glutathione disulfide (GSSG)
• Research focus: Redox chemistry, thiol biology, enzymology, and cellular-stress pathways

The formula and molecular weight above refer to reduced glutathione. Oxidized glutathione, salts, and other supplied forms have different compositions. The exact chemical form should be verified against the product label and batch-specific COA.

Scientific Background

Glutathione contains a reactive sulfhydryl group contributed by its cysteine residue. This thiol group allows GSH to participate in reduction-oxidation reactions and convert to GSSG under oxidative conditions.

The GSH/GSSG system is widely studied as part of cellular redox regulation. Glutathione also serves as a substrate or cofactor in reactions involving glutathione peroxidases, glutathione reductase, and glutathione S-transferases. These enzyme systems are investigated in connection with peroxide metabolism, electrophile conjugation, cellular defense mechanisms, and biochemical homeostasis.

Laboratory findings involving glutathione should not be represented as proof of therapeutic, detoxification, or disease-related effects in humans.

Research Applications

Glutathione may be studied in controlled laboratory settings involving:

• GSH/GSSG ratio analysis
• Cellular redox and oxidative-stress research
• Thiol-dependent biochemical reactions
• Glutathione-related enzyme assays
• Electrophile-conjugation studies
• Compound identity, purity, and stability analysis
• Analytical and cellular-metabolism research

Storage and Handling

Store according to the conditions stated on the batch documentation. Protect from heat, moisture, contamination, unnecessary light exposure, and oxidizing conditions. Handling should be limited to qualified laboratory personnel using appropriate research procedures.

Research Use Only

For Research Use Only. Not for human or veterinary use. Not intended for diagnostic, therapeutic, clinical, cosmetic, or household use. Not intended to diagnose, treat, cure, mitigate, or prevent any disease or medical condition. Not a drug, food, cosmetic, or dietary supplement.